4D+ Genome Lab

Data Guided Control

Research theme: The work in our lab is at the interface between mathematics and human genome biology. In particular, we study the dynamics of genome organization in human cells. From these data, our goal is to understand genome reprogrammability (=controllability).

Principal Investigator: Indika Rajapakse (Computational Medicine and Bioinformatics, Mathematics)
Lab manager: Walter Meixner
Postdocs: Haiming Chen, Geoffrey Patterson (Computational Medicine and Bioinformatics)
Ph.D. students: Laura Seaman, Scott Ronquist (Computational Medicine and Bioinformatics)
Undergraduate student: Stephen Lindsly (Computer Engineering)

Funding

Diversity and Complexity of Biological Networks
The National Institute of Diabetes and Digestive and Kidney Diseases
Defense Advanced Research Projects Agency

Research

Data-Guided Control

Spectral identification of topological domains (TADs)

Contact Information

Department of Computational Medicine & Bioinformatics
1600 Huron Parkway
NCRC Building 520,
Rm. 3392
Ann Arbor, MI 48105
734-763-0782